| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K875 | 新沂 | 02:25 | 阜阳 | 07:37 |
| K878 | 新沂 | 02:25 | 阜阳 | 07:37 |
| K8411 | 新沂 | 07:44 | 阜阳 | 12:15 |
| K8414 | 新沂 | 07:44 | 阜阳 | 12:15 |
| K491 | 新沂 | 12:54 | 阜阳 | 17:09 |
| K494 | 新沂 | 12:54 | 阜阳 | 17:09 |
| K1623 | 新沂 | 18:35 | 阜阳 | 22:41 |
| K1626 | 新沂 | 18:35 | 阜阳 | 22:41 |
| K611 | 新沂 | 19:13 | 阜阳 | 23:50 |
| K614 | 新沂 | 19:13 | 阜阳 | 23:50 |
| K1066 | 新沂 | 19:20 | 阜阳 | 00:33 |
| K1067 | 新沂 | 19:20 | 阜阳 | 00:33 |